Jit Pro Health Tips and Product Reviews

Having Something Stolen from Me Woke Me Up to the Need for Security

Home security never seemed to be a problem when I lived at home with my parents. We lived in an upscale neighborhood built around the edges of a beautiful mountain. It was somewhat hard to get in and out of the neighborhood quickly, so burglars were not enticed by our location. Things changed when I got an apartment of my own in the center of our city where many people have easy access to the location where my apartment building is located. Previously, it never occured to me that people would choose apartments to burglarize, but I’ve learned that criminals find apartments to be easy pickings.

I realized that I was burglarized when I went out to get my bike off my balcony one morning so that I could bike to work, but it was missing. It confused me at first because I live on the second floor of my building. Other units across the way face my balcony. I scratched my head as I looked at the blank space where my bike usually sat on the balcony each day and night. Then, a woman on the balcony across from me came out and said that she heard that someone had shimmied up to my balcony and stolen my bicycle, yet no one had bothered to call the police.

The theft happened over night, and it alarmed me to think about a criminal being so close to me while I slept. He or she could have easily opened my sliding glass door and come into my bedroom. It also bothered me that someone had seen the theft happen, but they didn’t care about calling the police while it was happening. This led me to realize that they only way that I would remain safe is to purchase an alarm system as soon as possible.

The first aid method of heart disease

Heart attack is often in public places, there are no medical staff, and many people do not know what to do. Time for heart attack is very precious, and it is very important how to perform effective first aid. If you have a heart attack on your side, it is better to know about some of the first aid for heart disease. At the time of the crisis, it is necessary to respond in time to treatment and perhaps it will save a life. Here are some specific steps for a heart attack emergency.

Heart disease is congenital and acquired

The incidence of heart disease has risen in the last 20 years, which is related to many factors, such as high-salt and high-fat diets, lack of exercise, obesity, and mental factors. These factors have caused a gradual increase in the incidence of heart disease, especially the incidence of coronary heart disease has increased significantly.

The general classification of heart disease is relatively simple. One is congenital and the other is acquired. Congenital is a congenital heart disease. It refers to the abnormal anatomy caused by obstacles in the formation of the heart and large blood vessels during the human embryonic development, or the heart that cannot be closed after the birth. The congenital part is only a part, and more is acquired. Acquired include several major categories, the most common is coronary heart disease is mainly based on coronary artery disease; followed by valvular disease, such as rheumatic heart disease, degenerative heart disease in the elderly; and myocardial disease, its classification is more extensive There are other heart problems caused by thyroid hyperthyroidism, high blood pressure and other factors.

Weary and flustered, wary of heart disease, early treatment to avoid accidents

The symptoms of heart disease are extensive. Regardless of the type of heart disease, most of the symptoms of acquired heart disease are insignificant except for congenital heart disease. Common symptoms are: fatigue, activity feel shortness of breath; palpitation and palpitations; chest tightness, chest pain, common symptoms of coronary heart disease; heart failure caused by heart failure, resulting in lower extremity edema, abdominal distension, loss of appetite; coughing, sleeping until midnight felt belching. In general, the symptoms of heart disease are varied, and some are based on other manifestations such as cough and edema. Coughing many people thinks that respiratory problems, but it is also a manifestation of heart health.

Although most of the heart attacks have no signs, some heart attacks still have some symptoms. For example, coronary heart disease has chest tightness and chest pain some time before the onset of the disease. Many people do not pay much attention to it. In addition, there are cold sweats, black eyes, and dizziness before the onset. As long as you are diagnosed with a heart attack, you should immediately see the above symptoms. Many people who do not have the diagnosis will ignore these symptoms. Through publicity, more people will know that these symptoms are related to the heart. To seek treatment as soon as possible, you can avoid accidents.

Four types of people are at high risk of heart disease

There are four risk factors for heart disease: smoking, high blood pressure, hyperlipidemia, and diabetes. These individuals have a greater risk of heart disease. Those who are more broad may include obesity, low exercise, and high mental stress.

Heart disease check is not complicated

Cardiac examination is not very complicated, such as arrhythmia to be a simple electrocardiogram can be diagnosed; congenital heart disease, valvular disease can be diagnosed basically by cardiac ultrasound; for coronary heart disease can be exercise ECG, cardiac radionuclide scan, CT examination, blood vessels Imaging, coronary angiography, etc. can all be diagnosed. There are even some cardiologists who can check through physical examinations. If auscultation can detect murmurs, so some routine examinations can diagnose heart disease.

Heart disease people go out to do it

Travelling with heart disease patients must first take measures and go out for exercise. Pay attention to rest and avoid fatigue. Because heart function is limited, fatigue may aggravate or induce heart disease. Second, do not go to remote places and places away from urban hospitals. It is difficult to get timely treatment; in the end, it is necessary to bring medicine and disease diagnosis information with you, because some patients become unconscious at the time of onset. If this time the body carries these data, it will be convenient for us to understand the history of the past and it will be of great help to the treatment.

People around to have a heart attack to make a judgment before doing cardiopulmonary resuscitation

Heart attack is often in public places, there are no medical staff, and many people do not know what to do. First of all to judge, to determine whether the patient has a heartbeat, you can touch the big artery fluctuations, usually touch the carotid artery, 3 cm in the side of the throat, can feel the fluctuations indicate a heartbeat. If there is no heartbeat, cardiopulmonary resuscitation should be carried out. First, chest compressions must be performed, then the airway must be opened, and finally artificial respiration.

Prepare beforehand: Before the cardiopulmonary resuscitation, the patient should be restored to supine position. When recovering, care should be taken to protect the injured spine. First put the patient’s legs in a supine position, then use one hand to hold the neck of the patient, and the other hand to flip the patient’s trunk.

Chest compression: The first-aid person’s arms are located in the lower 1/3 of the patient’s sternum, the double elbow joints are straightened, and the upper body weight is used to press down vertically, and the intermediate-body weight adults should have a depth of more than 5 cm, and then quickly relax and relieve the pressure. Allow the chest to reset itself. Repeatedly rhythmically, the pressing time is approximately equal to the relaxation time, and the frequency is no less than 100 times per minute.

Open Airway: Clean up the first aid person placing one hand on the patient’s forehead and tilting his head back, and lift the back neck with another hand or lift the lower jaw to keep the airway open. For those suspected of having a neck injury, only the lower jaw can be lifted and the head can not be thrown back; if there is a suspected airway foreign body, the patient should be surrounded by the back of the patient’s upper abdomen with force and squeezing.

Artificial Respiratory Breathing: With the patient’s head raised, the rescuer closes the nostril (or lip) with a hand, then takes a deep breath and quickly blows into the patient’s mouth (or nose), then relaxes the nostrils. (or lips), repeat this every 5 seconds until spontaneous breathing resumes. Each inspiratory interval of 1.5 seconds, during this time the rescuer should take a deep breath in order to continue mouth-to-mouth breathing until the medical staff arrived.

When there is only one first-aid person performing CPR on the patient, it should be done with 30 chest cardiac presses every time, alternating with 2 artificial respirations.

How to treat emergency fractures in children?

How to deal with emergency treatment of pediatric fractures

1. If there are skin wounds and bleeding, remove visible dirt and pressurize it with clean cotton or towels.

2. When open fractures of the extremities (bone fractures exposed through the wound) are bleeding, they must not be misused by cords or wires. A wide cloth strip and rubber hose can be used to tie the wound. Do not tie it too tightly so that it does not bleed, and relax for an hour or two for an hour or two. Upper body strapping tourniquet should be on the upper 1/3 of the upper arm to avoid damaging the phrenic nerve.

3, upper limb fractures can be fixed with wood or wood root, cardboard, and then use a bandage or rope hanging from the neck. Fractures of lower limbs can be tied with wooden or wood roots, or they can be tied together for fixation. Note: If the child is too young, it is best not to fix it so that it will droop naturally and it will be taken to the hospital in time.

4, pelvic fractures, with a wide cloth sticking pelvis, the patient supine, knee half flexion, knee pads under a pillow or clothing, in order to stabilize the body, reduce the shaking.

Clinical manifestations of pediatric fractures

1, systemic performance

(1) Shock For multiple fractures, pelvic fractures, femoral fractures, spinal fractures, and severe open fractures, patients often experience shock due to extensive soft-tissue injuries, massive bleeding, severe pain, or concurrent visceral injury.

(2) Fever There is a large amount of internal hemorrhage at the fracture site. When the hematoma is absorbed, the body temperature rises slightly, but generally it does not exceed 38°C. The risk of infection should be considered when the open fracture body temperature rises.

2, partial performance

Local manifestations of fractures include specific signs and other manifestations of fractures.

3, the unique signs of fracture

(1) Malformation

Displacement of the fracture can change the appearance of the affected limb, mainly manifested as shortening, angulation and prolongation.

(2) Abnormal activities

In normal conditions, the limbs are unable to move and abnormal activities occur after the fracture.

(3) Bone flu or bone rubbing

After the fracture, the two fractures end up rubbing against each other and can produce bone fricative or bone rubbing sensations.

As long as one of the above three signs can be diagnosed, the three types of signs do not eliminate the possibility of fracture, such as inset fractures and fractures. Under normal circumstances, do not check the above signs for diagnosis, because it will increase the damage.

There are many benefits for women to drink yogurt

Yogurt is not only delicious, but there are many benefits for women to drink yogurt, such as preventing constipation, promoting digestion, boosting immunity, preventing infection, and so on.

The benefits of a woman drinking yogurt

1, to prevent colds

Eating yoghurt can reduce the chance of upper respiratory tract infection by 12%. People who drink yoghurt often have a much lower chance of catching cold than those who do not drink yoghurt.

2, to promote digestion

Women who have dyspepsia can usually drink yoghurt at an appropriate level. It can promote the secretion of gastric juice, thereby increasing appetite and enhancing digestion.

3, to prevent constipation

Many women have constipation. You may not know that preventing constipation is one of the benefits of yoghurt for women. Yogurt promotes intestinal peristalsis and bacterial growth by producing a large amount of short-chain fatty acids to change osmotic pressure and prevent constipation.

4, reduce the stimulation of acne, relieve acne symptoms

The high activity inorganic mineral trace element zinc, which is rich in yoghurt, and certain derivatives of vitamin A and vitamin e, help the conversion and excretion of certain toxic substances in the body, reduce the stimulation of acne, relieve the symptoms of acne, and help heal.

Yogurt “forbidden”

1, not the bigger the better

Many people like to drink yoghurt, even treat it as a drink, a few bottles a day. Experts pointed out that drinking yogurt is not as good as possible, especially for yogurt with health food status, but it needs to be controlled.

Xiao Bian sees that the suitable population identified by Mengniu Guanyi Milk is “intestinal dysfunction, immunocompromised persons” and the usage and dosage are “two times per day, one cup at a time.” Experts pointed out that health foods are functional foods with specific effects and cannot be eaten in large quantities like ordinary foods. Instead, they should pay attention to the right people and dosage, and do not eat too much.

2, do not drink after an empty stomach

Because stomach acid has a bactericidal effect, it is best not to drink yogurt containing probiotics on an empty stomach. Generally, it is better to drink after meals. In order to retain the activity of probiotics contained in yogurt, it is best to drink hot drinks before and after drinking yogurt.

3, only refrigerated can not be heated

Many people know that the thousands of “bacteria” in yogurt are good things, but they don’t know how to keep them. Professor Nan Qingxian introduced that when yoghurt was just produced, it was live bacteria, and only the cold storage could keep the live bacteria well. Others like to hot drink yoghurt, this practice is even more violent.

When yogurt is good

1, the most calcium drink yogurt at night

From 12 o’clock in the morning to the early morning, when the body’s blood calcium content is the lowest, it is beneficial to the absorption of calcium in food. At the same time from 12 o’clock in the evening to midnight, there are fewer factors affecting calcium absorption in the human body.

2, the use of computers to drink yogurt anti-radiation effect is most obvious

Yogurt also has the effect of reducing radiation damage and inhibiting the decrease in the number of human lymphocytes after radiation, so it is better to receive yogurt after receiving radiation.

3, drink yogurt in the afternoon to rejuvenate

Tyrosine in yoghurt is of great help in alleviating human fatigue caused by excessive psychological stress, high tension and anxiety. After lactic acid bacteria fermentation, the proteins, peptides, amino acids and other particles in the yoghurt become minute, the content of free tyrosine is greatly increased, and absorption is easier. Having a cup of yoghurt in the afternoon allows the office worker to relax and is full of energy throughout the afternoon, which is more conducive to improving work efficiency.

4, drink yogurt after dinner is best for the stomach

If you drink yogurt in an empty stomach, it is easy to stimulate the emptying of the gastrointestinal tract. The nutrients in the yogurt can not be fully digested and then discharged. After a meal, you can reduce irritation, allow the yogurt to be absorbed slowly in the stomach, and it can help digestion. .

These vegetables eat too much to cause cancer

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Anti-cancer diet has become common sense in our lives, but eating the wrong food can also cause cancer. For example, vegetables that we eat every day, many vegetables can prevent cancer, and some vegetables may cause cancer. Today, what are the anti-cancer and cancer-causing vegetables?

What kind of vegetables are good for preventing cancer?

tomato.

Tomatoes contain large quantities of lycopene and carotenoids. They are antioxidants, especially lycopene, which neutralize free radicals in the body. They are good for anti-gastric cancer and cancer of the digestive system, and they are also effective in preventing breast cancer and prostate cancer.

sweet potato.

The sweet potato contains hydrogen steric and chemical compounds that help prevent colon and breast cancer.

garlic.

People who eat raw garlic, the incidence of gastric cancer is very low, because garlic can significantly reduce the content of nitrite in the stomach, and this is a very important cause of gastric cancer. Those who regularly eat onions have a 25% lower incidence of gastric cancer than those who eat less or do not eat onions. In addition, eating less pickled foods, smoked fish and grilled fish is also a good way to prevent stomach cancer.

Cabbage vegetables.

The glucosinolate compounds contained in cabbage vegetables have an inducing effect on a detoxifying enzyme in the human body. Regular consumption can prevent the occurrence of gastric cancer, lung cancer, esophageal cancer and colon cancer.

mushroom.

It has the reputation of “anti-cancer first cuisine”, such as mushroom, mushroom, shiitake mushroom, etc. It contains polysaccharide anti-cancer active substances that can promote the formation of antibodies, make the body immune to tumors, and inhibit the growth of tumor cells. It is beneficial to many kinds of cancers including lymphomas and colon cancers, especially for liver cancer patients.

onion.

Eating onions can reduce the content of nitrite in the stomach, and it is important that onions contain a substance called quercetin, a natural anti-cancer substance. Research shows that people who regularly eat onions have a 25% lower incidence of gastric cancer than those who eat less or eat less onions, and a 30% lower risk of death from stomach cancer.

So what are the vegetables that cause cancer?

Which vegetables cause cancer

Fresh fungus:

Fresh fungus contains a light-sensitive substance that, when consumed by humans, is distributed to the epidermal cells along with the blood circulation. After being exposed to the sun, it can cause solar dermatitis. This toxic light-sensitive substance is also easily absorbed by the throat mucosa, causing throat edema.

Green tomatoes:

Immature tomatoes contain alkaloids that can cause poisoning after human consumption. So be sure to eat bright red tomatoes.

Germinating potatoes:

Germinated potatoes produce large amounts of solanine, which can be poisoned by humans. When eating sprouted potatoes, the green parts of the buds and shoot roots and potatoes must be dug out and soaked in clean water for more than 2 hours.

Fresh lentils:

Fresh lentils contain saponins and alkaloids, which are poisonous but dissolve when exposed to heat. Before eating, apply boiling water to dip through or over the oil, or dry until it is discolored.

Fresh broad beans:

Some people lack an enzyme in their bodies, which can cause allergic hemolytic syndrome after eating fresh fava beans. Symptoms are fatigue, anemia, jaundice, hepatomegaly, vomiting, fever, etc. If you do not rescue in time, you will die from extreme anaemia.

In addition, the leftover vegetables can also cause cancer. Associate Professor Chen Chaogang, Clinical Nutrition Division, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, because the nitrate content of vegetables is relatively high, especially cabbage, leeks, and nitrite will be formed during the preservation process. Bacteria produce a reaction that converts to ammonium nitrite, which is a carcinogenic substance. Eating too much overnight vegetables, and carcinogens accumulating in the body, can be detrimental to your health.

Prevent cancer, remember which vegetables can eat, and which vegetables can’t eat.

 

 

The most hated people in the United States have been convicted

The US court ruled that the former President of the US Turing Pharmaceutical Company, who has been called “the most hated person in the United States” for driving up drug prices, has spent more than $40 million on fraudulent hedge fund investors and manipulated its biotech. The company’s stock price of Retrophin was convicted of fraud last August. The New York Federal Court of Justice sentenced Shakrani to 7 years in prison and a fine of 75,000 U.S. dollars.

 

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According to reports, Martin Shkreli made a fortune in 2015 by raising the price of a Daraprim, a life-saving drug for the treatment of malaria and AIDS, from US$13.5 to 50 to US$750.

However, the judge indicated that the sentence was not related to Sacrani’s personal speech and other acts.

The 34-year-old Shakurani was arrested in December 2015 on suspicion of a similar Ponzi scheme in securities fraud. He was later charged with eight counts of securities fraud, conspiracy to commit securities fraud, and complicity in telecommunication fraud. . In August last year, the jury found that three of the charges were established.

Sacralny’s previous psychological assessment showed anxiety, depression, and personality disorder. The judge ordered him to receive mental health treatment.

In the courtroom, Shakurani stated that he stupidly committed mistakes because of his position and reputation, and he confided in the trust of customers, apologized to them sincerely, and hoped that he would serve the community after his release from prison.

Constipation is the enemy of heart disease

Patients with constipation have difficulty in defecation, and they often use too much force to cause increased abdominal pressure and increase in blood pressure. At the same time, heart rate increases, resulting in increased oxygen consumption in the myocardium, resulting in severe and prolonged acute ischemia and even development of the myocardium. Myocardial infarction. When constipation patients bowel movements, they will often hold their breath and squeeze the viscera, causing the heart to rupture, dissecting aneurysm or rupture of large blood vessels, etc., which is also life-threatening. For heart disease, constipation is one of the risk factors for acute myocardial infarction. When the patient is forced to defecate, the vascular pressure increases, the blood flow speeds up, and it is easy to flush the plaque attached to the blood vessel wall into the blood stream to block the blood vessels, cause acute myocardial infarction, and even cause sudden death.

In addition to inducing severe heart disease, constipation also has multiple hazards such as increased acne, induced anal fissure, abdominal wall spasm, and gastrointestinal nerve dysfunction. Therefore, the elderly (especially those with poor heart) must pay attention to the prevention and treatment of constipation. Use the following method. 1. Adhere to participate in exercise; 2. Develop a good bowel habit: You can practice daily defecation once in the morning. Even if you do not feel comfortable, you can sit still for a while to form a conditional reflex and pay attention to creating a quiet and comfortable environment. Choose a sitting toilet; 3. A reasonable diet: eat more foods containing crude fiber and vegetables, fruits, beans, drink plenty of water, at least 1500 ml per day, especially in the morning or before a meal to drink a glass of warm water, you should also eat some with Runchangtong The food that will act, such as black sesame seeds, honey, bananas, etc.; 4. Active treatment.

Finally, we need to remind the elderly that they must pay attention to their own physical health. Regular medical examinations and timely treatment. Elderly people with heart disease should carry emergency medicine such as nitroglycerin and Suxiao Jiuxin Pill. “Life Times” reporters also learned that Chen had almost never had physical examinations before, had no knowledge of his heart and had never taken emergency medicine with him. Chen Lao has habitual constipation, but he does not pay attention and has not taken any effective treatment measures. Otherwise, this accident can be avoided or the emergency is successful.

Ten years of worst flu raging in the United States

On March 8th, the US “Wall Street Journal” website published an article titled “The Middle Ages of the United States under the Flu”. This was the most serious flu epidemic in the United States in 10 years. Thousands of people were hospitalized with the flu and they usually seemed to be healthy. Adults are also unable to escape this robbery. Some middle-aged and middle-aged people have died of flu.

The article said that on January 29th, second-grade teacher Heather Holland returned home from work and felt a bit uncomfortable.

Heather’s husband, Frank Holland, said: “She was only a blind man that day. It sounded a bit dumb.” For a mother who has a full-time job, this discomfort is easily overlooked at first. In the next few days, Heather made several seemingly irrelevant decisions, including the fact that he did not buy prescription drugs for doctors because he was too expensive. Then, at the age of 38, she suddenly suffered a worsening condition and eventually had to be hospitalized for treatment. Her life was in critical condition. On February 4, Heather died. When she came home from work, her voice was a bit dumb, and it was only six days at the end of her life.

Heather caught up with the worst flu pandemic in the United States in 10 years, and her fight with the flu was one of the most striking cases. The flu hit the United States by surprise and the flu vaccine was so weak that it could not stop the rampant virus.

According to the article, after a few days of headache, fever, and coughing, most people’s immune system will overcome the virus and restore health. However, in 2018, thousands of Americans were hospitalized for pneumonia and other complications, including adults who did not have basic diseases and seemed to be healthy.

According to the Centers for Disease Control and Prevention (CDC), the hospitalization rate in the United States this winter is the highest since 2010, and the number of influenza cases reported is as high as during the 2009 global influenza outbreak.

The proportion of deaths caused by influenza and pneumonia to the total number of deaths in the United States has risen to one of the highest levels in the past few flu seasons. According to the CDC, between 12,000 and 56,000 people in the United States die from the flu each year, and it is estimated that the number of deaths during the flu season will be at the upper limit. Old people and young children are at greatest risk.

“This is not an ordinary cold,” said Tim Uyeki, chief medical officer of the CDC Flu Department.
Dr. Uyeki said that when the body’s immune system is overreacting, complications may occur because excessive immune responses can easily trigger radical inflammatory responses that lead to viral pneumonia, organ damage, or sepsis. He said that after suffering from the flu, bacteria sometimes invade the blood stream more easily, resulting in bacterial pneumonia that can cause sepsis.

In both cases, the condition of the flu patient may rapidly deteriorate with high fever, or abnormally low body temperature, and shortness of breath.

According to the CDC, the most important influenza virus in the United States this year is the menacing A/H3N2 flu. The facts of the past few weeks have proven that both A and B can pose a deadly threat.

According to studies conducted by the CDC and other countries, this year’s vaccine is not very effective, but it can reduce the flu symptoms.

Karlie Slaven’s father said that her daughter did not get a flu shot this year. He is now trying hard to advocate that people get flu shots.

In mid-January, Sleven was still taking care of her two children. Then one day, the 37-year-old executive from Plainfield, Indiana, suddenly caught the flu virus. On the second day after being diagnosed with flu, Sleven began to have difficulty breathing. For this she went to the hospital to see the emergency department. Her father, Karl Illg, said that the X-ray showed Sleven nothing. The doctor gave her medicine and she went home.

Ilger said that the son-in-law Michael Slaven was a member of the National Guard. Due to the assignment, she had to leave home at 5 am the next morning. A few hours later, Sleven sent a message to his father for help. The father said: “She really can’t speak.”

Ilger and his wife went to their daughter Sleven’s house. The wife sent her daughter to the hospital emergency room, and Ilg left behind her 11-year-old grandson and her 9-year-old granddaughter.

A few hours later, Irga’s wife called to let Ilge take the grandson to the hospital. Sleven was critically ill and her husband received a call on the way to the mission and quickly returned.

Irga said that he did not expect her daughter’s condition to deteriorate so quickly. Two days ago, it was just a common cold, and after she arrived at the hospital she could barely lift her eyelids.

The next morning, Sleven died. It was less than three days since she learned that she had the flu and died in a hurry.

Japanese scientists mass-produce transgenic pigs Organs can be transplanted to humans

British media said that in the near future, we may be able to rely on pigs to carry out life-saving organ transplantation.
According to a report on the British “Daily Mail” website on March 8, a team of Japanese scientists said that they have already cultivated pigs that have genetically modified organs that can be transplanted to humans.

It is reported that these pigs were the first animals to be cultured for xenotransplantation. Xenotransplantation refers to the successful transplantation of animal organs and tissues into humans.

According to the Japan’s “Yomiuri Shimbun” report, the team includes researchers from Meiji University and Kyoto Prefectural University, who hope to provide these pigs to a private company early next year.

It has been found that pigs are ideal objects for studying how to treat or prevent certain human diseases.
The leader of this research, Meiji University’s Professor Naoji Luizhi, spent several years studying transgenic pigs as a model of human genetic disease.

Now he has developed a way to grow organs that can be transplanted into the body in pigs.

According to the report, scientists first collected induced pluripotent stem cells from a patient and injected these human stem cells into “custom” pig embryos. These embryos had previously been genetically modified and did not have the ability to grow out of the pancreas.
The study stated: “This creates a ‘gap’ or ‘space’ that can be occupied later.”

Subsequently, stem cells enable human organs to grow in porcine embryos.
Although the study focused on creating the pancreas, scientists said that this process may be applicable to many different organs.

Reported that before the sows gave birth, the scientists removed the uterus and removed the piglets in a pathogen-free room.

The scientists obtained a total of 17 piglets.
They fed the piglets with sterile artificial milk and raised them for about a month.

Scientists must adhere to strict safety and health guidelines when implementing artificial reproduction techniques.
According to the Yomiuri Shimbun, some guidelines require that pigs be kept in a clean and protected environment. 40 viruses should be tested to prevent infection and ensure patient safety.

They hope that pigs can save those who suffer from organ failure and cannot find transplant organs.
Long Island than Lu Zhi said: “In the near future, patients do not have to wait.”

The Joint Organisation of Organisation of Organ Sharing said that on average, 20 Americans die each day while waiting for an organ transplant.
Reported that for more than a decade, scientists have been studying how to use the “model animal” with a transplantable organ to save human life.

In addition to cultivating animals used for organ transplants, Nagashima Tokihiro “borrowed the body of pigs” to study hereditary human diseases, including diabetes, amyotrophic lateral sclerosis (commonly known as degenerative frost), hereditary metabolic disorders, and muscles. Malnutrition and so on.

Longlu Zhilu explained: “I believe that the disease model pigs we have developed are very useful for the development of therapies and drugs for these patients.”

He also said: “My dream is to see with my own eyes that some patients are cured through our therapy.”
According to reports, pig-to-human xenotransplantation has been carried out in countries such as New Zealand and Russia. However, this practice has also been opposed by some scientists and bioethics scientists who believe that inter-species embryos “are detrimental to our humanity.”

The report said that despite this, the National Institutes of Health in 2016 suspended the suspension of funding for these controversial experiments. This means that scientists can use federal government funds to make transgenic embryos under certain closely monitored conditions. This kind of embryo is also called a chimera.

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Harvard University and other research institutes and company teams use the CRISPR-Cas9 gene editing technology to eliminate the endogenous retrovirus (PERV) contained in the pig genome, which is considered as a major breakthrough in the use of pig organs for human transplantation. .

The removal of PERV may solve two problems. First, if the pig organ can be transplanted into the human body, the risk that the virus may cause people to be infected is ruled out. Second, the immune rejection after the organ transplant that the virus may cause is eliminated.
Transplanting animal organs to humans is a heterogeneous (peace) transplant that is significantly more complex than adopting human organs (allogeneic homografts) and has more technical challenges. Although this is an aspect, it is far better than using human organs for transplantation, and it can only be a record or spare tire.

According to the principle of “Road to Rome”, on the one hand, it is explored as a path of organ transplantation. On the other hand, it focuses on transplanting human organs. At present, it mainly encourages more people to die. Donate organs afterwards.

Even if the pig’s PERV is cut off, the problems of safety and rejection still exist, and it is obviously more than that of transplanting human organs. Because it is a heterogeneous organ, there are many more immunogenic substances (molecules) on the pig’s organs that can trigger immune reactions, and many problems such as immune rejection need to be resolved.

In addition, because it is a xenobiotic organ, the life span of the pig and the physiological functions of the organ are also different from those of humans, which may make it difficult to ensure that the organ transplanted to the pig has the same physiological functions as the human organ.

At present, the longest survivors of human liver transplants have surpassed 33 years, and kidney transplant recipients can survive longer. The longest survival time of living kidney transplant patients in the world is nearly 40 years (non-relative donor kidneys in China The maximum survival period for transplantation is 27 years). Measured only by the number of years of survival, it would have to be several times more than transplanting human organs, which obviously would create more insecurity.

In addition, because of the heterogeneous organs, the dose of anti-immune rejection drugs taken after the rejection reaction may be very large, which may affect the quality of life of the recipient and the life span of the recipient.

The greatest motivation for using animal organs for transplantation is to solve the problem of organ supply. If we can solve this problem, it is clear that adopting human organs is not only safer and more durable, but also ethically safer for recipients, at least not to worry that it is a human face. “Or “pig heart dog lung.”

No matter whether in China or in other countries of the world, the technology of organ transplantation is not a problem. The biggest problem is the rate of organ donation, and it also determines how many people’s lives can be saved by organ transplantation. Organ donation rate refers to the total number of organ donations in a country divided by the number of people in the country, that is, how many people per million people donate organs.

According to statistics from the World Health Organization’s Global Donation and Transplantation Observatory in 2016, the highest global donation rate is in Spain, at 43.8%; the United States is fifth, at 30.76%; China ranks 51, at 2.98%.

The National Conference on Human Organ Donation and Transplantation in 2017 revealed that nearly 300,000 volunteers for human organ donation have been registered in China, and over 12,000 cases of organ donation have been completed, and more than 34,500 large organs have been donated. At present, the number of donated human organs and the number of transplants are both ranked second in the world. However, the donation rate is also ranked behind. If the donation rate can be increased, human donor organs can fully meet the needs of organ transplantation.

Resolving this issue requires addressing why the Chinese don’t want to donate organs. A survey in 2011 showed that the highest proportion of all cadaveric remains was 33.1% after death, fearing that donated organs would cause organ sales of up to 30.1%; organ donation is not enough to know about organ donation That’s 20.69%; only 1% think it’s unnecessary to help others.

Therefore, by addressing the first three factors, China’s donor organs can meet demand. In the past two years, China has done a great deal of work on the fear of organ donation that causes the sale of organs. It has abolished the death of organ transplant recipients and increased the rate of organ donation.

Of course, this does not mean that the transplantation of animal organs for humans is not worth studying. If there is also a full-scale breakthrough in this respect, it will be a powerful supplement to organ transplantation.

Researchers from the United States, China and Denmark announced on the 10th that they have cultivated the world’s first live pigs that are not “toxic” to organ transplants and successfully solved the most important safety issues in the use of pig organs for human transplants. Millions of patients with organ transplants bring hope.

The research team led by eGenesis Inc. of the United States published thesis in the American academic journal “Science” on the same day. Harvard Medical School, China Yunnan Agricultural University and Aarhus University of Denmark were also involved in the research.

“Our work has fundamentally solved the risk of heterologous virus transmission in xenotransplantation,” said Yang Xin, co-founder and Chief Scientific Officer of eGenesis, who told Xinhua News Agency reporters. “The pigs are a groundbreaking breed of pigs. In the future, xenotransplantation is expected to be safely applied clinically.”

According to incomplete statistics, about 2 million people in the world need organ transplants, but the number of organ donations is much lower than demand. Porcine organs are considered to be suitable for transplantation due to their similarity in size and function to human organs.

In the 1990s, scientists tried xenotransplantation. However, experiments have found that pig organs contain not only immunological problems but also “poisonous” in the human body because the pig genome contains an endogenous retrovirus. In the end, both the World Health Organization and the U.S. government have explicitly ordered that all clinical trials of xenotransplantation be stopped before a solution is found, and the xenotransplantation industry has stagnated for many years.

In 2015, Dr. Yang, who was a postdoctoral fellow at Harvard University, successfully knocked out all potentially harmful viral genes in the pig genome with the aid of the gene editing tool CRISPR. This breakthrough was the first major breakthrough in vitro.

In the latest study, Yang Hao and others used CRISPR tools and small molecule drugs to successfully modify the 25 gene loci in the pig’s primary fibroblast genome. Then, like cultivating the world’s first somatic cell clone animal “Dolly” sheep, the researchers used a modified porcine fiber cell to create pig embryos and transplanted them into sows. Endogenous retrovirus inactivated pigs.

“At least in their 4 months of age, we did not observe a physiological difference between the modified pig and the normal piglet,” Yang said. “We will continue to reform the genome to solve the problem on the basis of these pig breeds.” Exclude the issue, strive to realize the clinical application of xenotransplantation as soon as possible, and save thousands of patients waiting for organ transplant.”

Darren Griffin, a professor at the University of Kent in the United Kingdom, commented that this work is a “major step” towards the realization of xenotransplantation. But he also cautioned that there are many variables in this area that include ethical issues that need to be addressed.

Professor Ian McConnell of Cambridge University in the United Kingdom also commented that this is a “first step full of hope”, but the development of xenotransplantation remains to be seen, because even if the problem of heterologous virus transmission is solved, it must be overcome. There are numerous obstacles such as immune rejection and physiological incompatibility of pig organs in the human body.

 

My Gram Moved to a Closer Apartment

The person I am closest to in the entire world is my grandmother. She practically raised me, and she has always been there for me no matter what is going on in my life or in hers. When my grandfather died, I wanted her to move in with me, but she did not want to completely give up her independence. I did the next best thing then, which was look for the best apartments in Forestville MD. She was living in an apartment over 200 miles away at the time, and I knew that I would only be able to visit once every month or so because of my work.

If she lived closer though, I would be able to see her as often as we both wanted. She has been here to visit me several times in the past and loves the area, so I figured I would look for an apartment to see if she would consider at least moving closer to me. Read more →